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Immortal enzyme-Nobel Prize
If ever humans become immortal, they would remember this year's Nobel. The 'telomere' is the thing to watch for in future for it determines when cells age and we die. If mastered, humans can live indefinitely or till they voluntarily wish to die.
THE NOBEL Prize in Physiology or Medicine for the year 2009 has been announced by Professor Göran K Hansson, Secretary of the Nobel Committee for Physiology or Medicine, on 5 October 2009. The Nobel Assembly at Karolinska Institutet has decided to award the Nobel Prize in Physiology or Medicine 2009 jointly to three scientists from United States Elizabeth H. Blackburn, Carol W. Greider and Jack W. Szostak for the discovery of "how chromosomes are protected by telomeres and the enzyme telomerase".

The three scientists have solved a major problem in cell division process that is, how the chromosomes can be copied in a complete way during cell divisions and how they are protected against degradation. Their research has found that an enzyme called telomerase is responsible for forming the ends of the chromosomes the telomeres which actually protects the chromosomes during the cell division.

 
The long, thread-like DNA molecules that carry our genes are packed into chromosomes, the telomeres being the caps on their ends. If the telomeres are shortened, cells age and, if telomerase activity is high, telomere length is maintained, and cellular aging is delayed. These discoveries can help shorten the life span of cancerous cells, which is presently considered to have eternal life. Hence discovery of telomerase can pave a new way for research in curing of deadly diseases like cancer and inherited diseases now known to be caused by telomerase defects, including certain forms of congenital aplastic anemia, in which insufficient cell divisions in the stem cells of the bone marrow lead to severe anemia.

Jack W. Szostak has been at Harvard Medical School since 1979. Elizabeth H. Blackburn, who holds both U.S. and Australian citizenship, is a professor of biology and physiology at the University of California, San Francisco. Carol W. Greider is a professor in the department of molecular biology and genetics at Johns Hopkins University School of Medicine in Baltimore. This is the first time when two women have been awarded the Nobel Prize in Physiology or Medicine in the same year even though ten women have won the prestigious medicine award since the first Nobel Prizes were awarded in 1901.

 
The award includes a 10 million kronor ($1.4 million) to be split by the winners, a diploma and an invitation to the prize ceremonies in Stockholm on December 10. In 1901, Emil von Behring was awarded the first Nobel Prize in Physiology or Medicine for his work on serum therapy, particularly for its use in the treatment of diphtheria. The Nobel Prize was founded by Alfred Nobel, a Swedish industrialist who invented dynamite. He established the prizes in his will in 1895. The first awards were handed out six years later.

COMMENTS (3)
Until just recently, Now Sports was selling a synthetic amino acid called L-Norvaline that has the effect of repressing the release of a particular stress enzyme called Arginase. When stressed, the body releases this enzyme that in turn derails the body's supply of Arginine into cell replication. Arginase also has control of DNA/RNA function and cell replication, which makes me wonder if there is a connection between Arginase and Telomerase. However, by repressing the release of Arginase, L-Norvaline allows the Arginine to be used for the purposes of Nitric Oxide production by the body. Nitric Oxide helps to cleanse the blood (ie a blood purifier that can help eliminate pathogens) as well as expand vascular pathways and so help prevent bacteria and other things from sticking to the sides of constricted vasuclar walls with pockets as can happen when Nitric Oxide levels fall. Because this effect of L-Norvaline is contrary to the production of Arginase, it might be that L-Norvaline is something to investigate with repressing the Telomerase release, as well. Hope this helps. God bless,
Until just recently, Now Sports was selling a synthetic amino acid called L-Norvaline that has the effect of repressing the release of a particular stress enzyme called Arginase. When stressed, the body releases this enzyme that in turn derails the body's supply of Arginine into cell replication. Arginase also has control of DNA/RNA function and cell replication, which makes me wonder if there is a connection between Arginase and Telomerase. However, by repressing the release of Arginase, L-Norvaline allows the Arginine to be used for the purposes of Nitric Oxide production by the body. Nitric Oxide helps to cleanse the blood (ie a blood purifier that can help eliminate pathogens) as well as expand vascular pathways and so help prevent bacteria and other things from sticking to the sides of constricted vasuclar walls with pockets as can happen when Nitric Oxide levels fall. Because this effect of L-Norvaline is contrary to the production of Arginase, it might be that L-Norvaline is something to investigate with repressing the Telomerase release, as well. Hope this helps. God bless,
Until just recently, Now Sports was selling a synthetic amino acid called L-Norvaline that has the effect of repressing the release of a particular stress enzyme called Arginase. When stressed, the body releases this enzyme that in turn derails the body's supply of Arginine into cell replication. Arginase also has control of DNA/RNA function and cell replication, which makes me wonder if there is a connection between Arginase and Telomerase. However, by repressing the release of Arginase, L-Norvaline allows the Arginine to be used for the purposes of Nitric Oxide production by the body. Nitric Oxide helps to cleanse the blood (ie a blood purifier that can help eliminate pathogens) as well as expand vascular pathways and so help prevent bacteria and other things from sticking to the sides of constricted vasuclar walls with pockets as can happen when Nitric Oxide levels fall. Because this effect of L-Norvaline is contrary to the production of Arginase, it might be that L-Norvaline is something to investigate with repressing the Telomerase release, as well. Hope this helps. God bless,
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