Current guidelines suggest that blood samples for lipid profiles should be obtained after a 9 to 12-hour fast. This requirement is not always practical for patients, who rarely present in a fasting state.
IT MAY not be necessary to fast overnight before a routine cholesterol profile check, according to a large community-based population study. It was done by Christopher Naugler, MSc, MD, of the University of Calgary in Alberta and published in the November 12 issue of the journal Archives of Internal Medicine.
In the study, the mean cholesterol subclass levels varied by less than 2% for total cholesterol and good HDL cholesterol, by less than 10% for calculated bad LDL cholesterol and by less than 20% for triglycerides.
Fasting is often inconvenient for patients and discourages compliance with routine screening programs.
On the other hand, eating before a cholesterol test can highlight insulin resistance, which is associated with worse post meal lipid clearance. High triglyceride levels after eating are predictors of insulin resistance. Total and good HDL cholesterol values do not change with food.
Current guidelines suggest that blood samples for lipid profiles should be obtained after a 9 to 12-hour fast. This requirement is not always practical for patients, who rarely present in a fasting state.