Vincenzo Natali's new flick 'Splice', is all set to hit the theatres on June 4, which has been directed under the banner of Warner Bros.

VINCENZO NATALI'S new flick "Splice", is all set to hit the theatres on June 4, which has been directed under the banner of Warner Bros.

 
"It was a photograph of something known as the Vacanti Mouse," Natali said during an interview to promote the film. "It was such a shocking image; and I just felt there was a film to be made from this."
 

The result is a science fiction-horror hybrid that blends elements of a very famous novel "Frankenstein" by Mary Shelly and "The Fly." "Splice" examines classic genre themes.
 
Oscar winner Adrien Brody and Sarah Polley are in the lead as Clive and Elsa (after Colin Clive and Elsa Lancaster, stars of the 1930s Universal "Frankenstein" films).
 
They are a romantically linked pair of genetic engineers whose work creating hybrid animal species has made them rock stars in their field. Egos and ambition collide and they create a rogue hybrid with human DNA, that they call Dren.
 
At first an all-CGI creature, Dren is portrayed in her rapidly maturing adulthood by French actress Delphine Chaneac. She is soon in the middle of a most tangled web woven by two doctors in way over their heads. The film takes some surprising - and quite disturbing twists.
 
"They are very courageous actors and I think they like to do experiment with new things," said Natali, who directed and co-wrote the film with Antoinette Terry Bryant and Doug Taylor.
 
"Dren is kind of a catalyst, I think, for opening up sides of Adrien and Sarah's characters that they have hidden away. Their darkest fears, their darkest desires emerge after they've created Dren."
 
They're not mad scientists, Natali says about the two lead characters. "But they are also a little bit immature. They're not fully prepared for what they've created, and they pay the price."
 
"Splice" is the type of smart sci-fiction that has been making a theatrical comeback of late. While it sports some impressive special effects work, with barely a half-dozen speaking parts and only a handful of locations, it is still a relatively low-budget affair.